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JoVE Journal Cancer Research
Моделирование метастазирования в мозг путем инъекции раковых клеток во внутреннюю сонную артерию
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Моделирование метастазирования в мозг путем инъекции раковых клеток во внутреннюю сонную артерию

Article DOI: 10.3791/64216-v • 10:01 min • August 2nd, 2022
August 2nd, 2022 •
1, 2, 1, 3, 2, *1,4, *1,5
1UQ Centre for Clinical Research, The University of Queensland, 2Centre for Advanced Imaging, Australian Institute for Bioengineering and Nanotechnology and ARC Training Centre for Innovation in Biomedical Imaging Technology, The University of Queensland, 3School of Biomedical Sciences, The University of Queensland, 4Mater Research and Mater Research Institute, The University of Queensland, 5Pathology Queensland, Royal Brisbane Women's Hospital
* These authors contributed equally

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Метастазы в мозг являются причиной тяжелой заболеваемости и смертности у онкологических больных. Большинство моделей метастазирования в мозг у мышей осложняются системными метастазами, смешивающими анализ смертности и результатов терапевтического вмешательства. Здесь представлен протокол внутренней каротидной инъекции раковых клеток, который продуцирует последовательные внутричерепные опухоли с минимальными системными опухолями.

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Исследование рака выпуск 186
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