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Capitolo 1
L'elica del DNA
Deoxyribonucleic acid, or DNA, is the genetic material responsible for passing traits from generation to generation in all organisms and most…
Il dogma centrale
The central dogma of biology states that information encoded in the DNA is transferred to messenger RNA (mRNA), which then directs the synthesis of…
Cellule procariotiche
Prokaryotes are small unicellular organisms in the domains Archaea and Bacteria. Bacteria include many common organisms such as Salmonella and…
Compartimentazione delle cellule eucariotiche
One of the distinguishing features of eukaryotic cells is that they contain membrane-bound organelles—such as the nucleus and…
L'Albero della Vita - Batteri, Archaea, Eucarioti
The “tree of life” describes the evolution of life and the evolutionary relationships between organisms. The root of the tree is the…
Mutazioni
Mutations are changes in the sequence of DNA. These changes can occur spontaneously or they can be induced by exposure to environmental factors.…
Genetica Evolutiva -Rapida o lenta?
The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do…
Grandezza del Genoma ed Evoluzione di Nuovi Geni
While every living organism has a genome of some kind (be it RNA, or DNA), there is considerable variation in the sizes of these blueprints. One…
Famiglie di Geni
Gene families consist of groups of genes proposed to have originated from a common ancestor. Typically these arise through events in which a gene or…
Tipi di Transfer Genetici tra Nuovi Organismi
Genetic transfer occurs when genetic information is passed from one organism to another. It occurs via two mechanisms: vertical gene transfer and…
Combinate le modifiche genetiche e chimiche del Capsid di vettori basati su Adenovirus Gene Transfer per schermatura e Targeting
Adenovirus vectors are potent tools for genetic vaccination and oncolytic virotherapy. However, they are prone to multiple undesired vector-host…
Singola goccia digitale Polymerase Chain Reaction per rilevazione completa e simultanea delle mutazioni nelle regioni di Hotspot
Droplet digital polymerase chain reaction (ddPCR) is a highly sensitive quantitative polymerase chain reaction (PCR) method based on sample…
Navigazione MARRVEL, uno strumento basato sul Web che integra la genomica umana e le informazioni di genetica degli organismi modello
Through whole-exome/genome sequencing, human geneticists identify rare variants that segregate with disease phenotypes. To assess if a specific…

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