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第1章
DNA螺旋
Deoxyribonucleic acid, or DNA, is the genetic material responsible for passing traits from generation to generation in all organisms and most…
中心法则
The central dogma of biology states that information encoded in the DNA is transferred to messenger RNA (mRNA), which then directs the synthesis of…
原核生物
Prokaryotes are small unicellular organisms in the domains Archaea and Bacteria. Bacteria include many common organisms such as Salmonella and…
真核细胞区室化
One of the distinguishing features of eukaryotic cells is that they contain membrane-bound organelles—such as the nucleus and…
生命之树 - 细菌、古细菌、真核生物
The “tree of life” describes the evolution of life and the evolutionary relationships between organisms. The root of the tree is the…
突变
Mutations are changes in the sequence of DNA. These changes can occur spontaneously or they can be induced by exposure to environmental factors.…
基因进化 - 快还是慢?
The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do…
基因组大小和新基因的进化
While every living organism has a genome of some kind (be it RNA, or DNA), there is considerable variation in the sizes of these blueprints. One…
基因家族
Gene families consist of groups of genes proposed to have originated from a common ancestor. Typically these arise through events in which a gene or…
生物间遗传转移的类型
Genetic transfer occurs when genetic information is passed from one organism to another. It occurs via two mechanisms: vertical gene transfer and…
联合遗传和化学衣壳改性腺病毒基因转移载体用于屏蔽和靶向
Adenovirus vectors are potent tools for genetic vaccination and oncolytic virotherapy. However, they are prone to multiple undesired vector-host…
单液滴数字聚合酶链反应对热点地区突变的综合和同步检测
Droplet digital polymerase chain reaction (ddPCR) is a highly sensitive quantitative polymerase chain reaction (PCR) method based on sample…
导航 MARRVEL,一种基于 Web 的工具,集成了人类基因组学和模型有机体遗传学信息
Through whole-exome/genome sequencing, human geneticists identify rare variants that segregate with disease phenotypes. To assess if a specific…

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