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Editorial

2009 Lindau Nobel ödüllü Toplantısı: Roger Y. Tsien, Kimya 2008

Published: January 13, 2010 doi: 10.3791/1575

Summary

Amerikalı biyokimyacı Roger Tsien, Yeşil Floresan Protein (GFP) keşfi ve gelişimi için Martin Chalfie ve Osamu Shimomura, 2008 Nobel Kimya Ödülü paylaştı. Tsien, yabani tip artan floresan GFP, fotostabilite artması, önemli bir uyarım tepe ve 488 nm bir kayma (FITC eşleştirme) önemli ölçüde düzeldi.

References

  1. Roger Y. Tsien - Autobiography [Internet]. , The Nobel Foundation. Available from: http://nobelprize.org/nobel_prizes/chemistry/laureates/2008/tsien-autobio.html (c2003).
  2. Nobel Lecture by Roger Y. Tsien- Media Player [Internet]. , The Nobel Foundation. Available from: http://nobelprize.org/mediaplayer/index.php?id=1070 (c2003).
  3. Davenport, D., Nicol, J. A. C. Luminescence of hydromedusae. Proc. R. Soc. 144, 399-411 (1955).
  4. Shimomura, O., Johnson, F. H., Saiga, Y. Extraction, purification and properties of aequorin, a bioluminescent protein from the luminous hydromedusan. Aequorea. J. Cell. Comp. Physiol. 59, 223-229 (1962).
  5. Tsien, R. Y. New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures. Biochemistry. 19 (11), 2396-2404 (1980).
  6. Heim, R., Cubitt, A., Tsien, R. Y. Improved green fluorescence. Nature. 373, 663-664 (1995).

Tags

Hücresel Biyoloji Sayı 35 GFP Yeşil Floresan Protein IFPS denizanası PKA Kalmodulin
2009 Lindau Nobel ödüllü Toplantısı: Roger Y. Tsien, Kimya 2008
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Tsien, R. Y. The 2009 Lindau NobelMore

Tsien, R. Y. The 2009 Lindau Nobel Laureate Meeting: Roger Y. Tsien, Chemistry 2008. J. Vis. Exp. (35), e1575, doi:10.3791/1575 (2010).

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