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JoVE Journal Biochemistry
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Measuring Biomolecular DSC Profiles with Thermolabile Ligands to Rapidly Characterize Folding and Binding Interactions
Journal (Biochemistry)
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Journal (Biochemistry)
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Cell Culture and Drug Treatment in the Human Embryonic Kidney 293 (HEK293) Cell Line (Video) | JoVE

Measuring Ubiquitylated, SUMOylated, and ADP-Ribosylated DNA-Protein Crosslinks

Article DOI: 10.3791/200208-v • 01:15 min • April 21st, 2023
April 21st, 2023 •
1
1Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health

Tags

DNA-protein Crosslinks Post-translational Modifications Repair Mechanisms Topoisomerase Inhibitors PARP Inhibitors Aldehydes Repair Pathways Post-translational Modifier Conjugated DNA Protein Crosslinks In Vivo Complex Of Enzyme Assay Rapid Approach To DNA Adduct Recovery Assay Immunofluorescence Specific Antibody Role Of Post-translational Modifications Quantitation Deubiquitylated SUMOylated ADP-ribosylated DNA Protein Crosslinks Kinetics And Formation
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