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Isolation and Normalization of DNA Containing Crosslinked Proteins (Video) | JoVE

Measuring Ubiquitylated, SUMOylated, and ADP-Ribosylated DNA-Protein Crosslinks

Article DOI: 10.3791/200209-v • 02:49 min • April 21st, 2023
April 21st, 2023 •
1
1Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health

Tags

DNA-protein Crosslinks Post-translational Modifications Repair Mechanisms Topoisomerase Inhibitors PARP Inhibitors Aldehydes Repair Pathways Post-translational Modifier Conjugated DNA Protein Crosslinks In Vivo Complex Of Enzyme Assay Rapid Approach To DNA Adduct Recovery Assay Immunofluorescence Specific Antibody Role Of Post-translational Modifications Quantitation Deubiquitylated SUMOylated ADP-ribosylated DNA Protein Crosslinks Kinetics And Formation
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