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Biochemistry

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JoVE Journal Biochemistry

Running the mAbscale Application to Calculate the Masses of Monoclonal Antibody-Based Protein Therapeutics (Video) | JoVE

TEV Protease-Mediated Elution and Denaturation Elution of the Chromatin Locus Purified from Saccharomyces cerevisiae (Video) | JoVE

Journal (Biochemistry)

TEV Protease-Mediated Elution and Denaturation Elution of the Chromatin Locus Purified from Saccharomyces cerevisiae (Video) | JoVE

Split-BioID — Proteomic Analysis of Context-specific Protein Complexes in Their Native Cellular Environment

Journal (Biochemistry)

Split-BioID — Proteomic Analysis of Context-specific Protein Complexes in Their Native Cellular Environment

Running the mAbscale Application to Calculate the Masses of Monoclonal Antibody-Based Protein Therapeutics (Video) | JoVE

A Python-Based Tool for Accurate Mass Calculation of Biotherapeutic Entities

Article DOI: 10.3791/200341-v • 03:04 min • June 16th, 2023

June 16th, 2023 •

Thomas Harkins^1,2, Li Cao¹, Kshitij Khatri^1,3

¹GlaxoSmithKline, ²Merck, ³Moderna

Tags

Open-source Framework Mass Calculation Antibody-based Therapeutic Molecules Biotherapeutic Masses Mass Spectrometry Protein Subunits Biopharmaceutical Development Computational Tools Protein And Peptide Molecular Weights Biotherapeutic Entities Modular Mass Calculation Routine Therapeutic Glycoproteins Monoclonal Antibodies Bispecific Antibodies Antibody-drug Conjugates Python-based Calculation Framework Vaccines Fusion Proteins Oligonucleotides Top-down Mass Spectrometry Data Standalone Desktop Application Graphical User Interface (GUI)

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