Login processing...

Journal / Cancer Research / /

JoVE Journal
Cancer Research

A subscription to JoVE is required to view this content.

JoVE Journal Cancer Research

Lentiviral Infection of MPNST Cells and Genomic DNA Isolation for Genome-Scale shRNA Screens (Video) | JoVE

Characterizing DNA Repair Processes at Transient and Long-lasting Double-strand DNA Breaks by Immunofluorescence Microscopy

Journal (Cancer Research)

Characterizing DNA Repair Processes at Transient and Long-lasting Double-strand DNA Breaks by Immunofluorescence Microscopy

Longitudinal Intravital Imaging Through Clear Silicone Windows

Journal (Cancer Research)

Longitudinal Intravital Imaging Through Clear Silicone Windows

Click here for the English version

Lentiviral Infection of MPNST Cells and Genomic DNA Isolation for Genome-Scale shRNA Screens (Video) | JoVE

Genome-Scale Screening to Identify and Compare Therapeutic Targets in Tumors

Article DOI: 10.3791/200478-v • 03:50 min • August 25th, 2023

August 25th, 2023 •

Brittany Turner-Ivey¹, Jody Fromm Longo², Dorea P. Jenkins², Stephen T. Guest³, Steven L. Carroll^1,2

¹Hollings Cancer Center, Medical University of South Carolina, ²Department of Pathology and Laboratory Medicine, Medical University of South Carolina, ³Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor

Tags

Genetisches Profiling Dropout-Screening auf Genomebene therapeutische Ziele Mausmodelle bösartiger peripherer Nervenscheidentumor Schwann-Zellen Neurofibromatose Typ 1 (NF1) Weichteilsarkom krankheitsfreie Überlebensraten Behandlungsoptionen entstellende Chirurgie Tipifarnib Ras-Signalinhibitor Erlotinib EGFR-Hemmer (Epidermal Growth Factor) Sorafenib vaskulärer endothelialer Wachstumsfaktorrezeptor (VEGF)-Inhibitor PDGF-Hemmer Raf-Inhibitor Funktionelles genomisches Screening Krebszelllinien zytoplasmatische Signalwege zielspezifische Therapien

X

Simple Hit Counter