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Journal / Cancer Research / Genome-Scale Screening to Identify and Compare… / Saggi citometrici di cellule MPNST testati con…
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Cancer Research

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JoVE Journal Cancer Research
Saggi citometrici di cellule MPNST testati con agenti terapeutici
Automated Multiplex Immunofluorescence Panel for Immuno-oncology Studies on Formalin-fixed Carcinoma Tissue Specimens
Journal (Cancer Research)
Automated Multiplex Immunofluorescence Panel for Immuno-oncology Studies on Formalin-fixed Carcinoma Tissue Specimens
A Preclinical Mouse Model of Osteosarcoma to Define the Extracellular Vesicle-mediated Communication Between Tumor and Mesenchymal Stem Cells
Journal (Cancer Research)
A Preclinical Mouse Model of Osteosarcoma to Define the Extracellular Vesicle-mediated Communication Between Tumor and Mesenchymal Stem Cells
 
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Saggi citometrici di cellule MPNST testati con agenti terapeutici

Genome-Scale Screening to Identify and Compare Therapeutic Targets in Tumors

Article DOI: 10.3791/200479-v • 01:30 min • August 25th, 2023
August 25th, 2023 •
1, 2, 2, 3, 1,2
1Hollings Cancer Center, Medical University of South Carolina, 2Department of Pathology and Laboratory Medicine, Medical University of South Carolina, 3Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor

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Profilazione genetica Screening dell'abbandono su scala genomica Bersagli terapeutici Modelli murini Tumore maligno della guaina dei nervi periferici Cellule di Schwann Neurofibromatosi di tipo 1 (NF1) Sarcoma dei tessuti molli Tassi di sopravvivenza libera da malattia Opzioni terapeutiche Chirurgia deturpante Tipifarnib Inibitore della segnalazione Ras Erlotinib Inibitore del fattore di crescita epidermico (EGFR) Sorafenib Inibitore del recettore del fattore di crescita endoteliale vascolare (VEGF) Inibitore del recettore del fattore di crescita derivato dalle piastrine (PDGF) Inibitore di Raf Screening genomico funzionale linee cellulari tumorali vie di segnalazione citoplasmatica terapie target-specific
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