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1Department of Physiology and Pharmacology,Loma Linda University School of Medicine, 2College of Natural and Agricultural Sciences,University of California, Riverside , 3Department of Anesthesiology,Loma Linda University School of Medicine, 4Department of Neurosurgery,Loma Linda University School of Medicine
Chapters
- 00:00Title
- 02:15Apparatus
- 03:00Presurgical Preparations
- 04:17ICH Surgery
- 07:39Behavioral Assessment
- 08:59Representative Results
Klinisk relevante dyremodeller av intracerebral blødning (ICH) for å utvide vår kunnskap om hjerneslag og å undersøke nye terapeutiske strategier. I denne studien beskriver vi og vurdere to ICH modeller som implementerer ensidige injeksjoner av enten autologt fullblod eller bakteriell collagenase i basalgangliene (corpus striatum) av mus.
Tags
ModelingIntracerebral HemorrhageMiceAutologous BloodBacterial CollagenasePreclinical ModelsTherapeutic StrategiesPathophysiologyHemorrhage InductionInjury ProgressionBlood Injection ModelCollagenase ModelBasal Lamina DisruptionPerihematomal EdemaNeurofunctional DeficitsDouble Injection ModelCD-1 MiceNeurofunctional DeficitsBrain Edema
