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The Rabbit Blood-shunt Model for the Study of Acute and Late Sequelae of Subarachnoid Hemorrhage: Technical Aspects
JoVE Journal
Medicine
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JoVE Journal Medicine
The Rabbit Blood-shunt Model for the Study of Acute and Late Sequelae of Subarachnoid Hemorrhage: Technical Aspects
DOI:

09:00 min

October 02, 2014

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Chapters

  • 00:05Title
  • 01:18Subclavian Artery Cannulation
  • 03:15Baseline Digital Subtraction Angiography
  • 03:48Installation of Intracranial Pressure and Cerebral Blood Flow Monitoring
  • 05:55Shunt Induction
  • 07:32Results: Representative Subarachnoid Hemorrhage (SAH) Analyses
  • 08:34Conclusion

Summary

Automatic Translation

The experimental intracranial pressure-controlled blood shunt subarachnoid hemorrhage (SAH) model in the rabbit combines the standard procedures — subclavian artery cannulation and transcutaneous cisterna magna puncture, which enables close mimicking of human pathophysiological conditions after SAH. We present step-by-step instructions and discuss key surgical points for successful experimental SAH creation.

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