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Der Einsatz von Reverse Phase Protein Arrays (RPPA) an Protein Expression Variation innerhalb der einzelnen Renal Cell Cancers erkunden
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Der Einsatz von Reverse Phase Protein Arrays (RPPA) an Protein Expression Variation innerhalb der einzelnen Renal Cell Cancers erkunden

Article DOI: 10.3791/50221-v • 12:23 min • January 22nd, 2013
January 22nd, 2013 •
1, 1, 1, 2, 3, 4, 4, 1,5, 6, 7, 1,2, 1
1Edinburgh Urological Cancer Group, University of Edinburgh, 2School of Medicine, University of St Andrews, 3Division of Pathology, University of Edinburgh, 4MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, 5Department of Pathology, Western General Hospital, 6Breakthrough Breast Cancer Research Unit, University of Edinburgh, 7St Bartholomew's Cancer Institute, Experimental Cancer Medicine Centre, Queen Mary University of London

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RPPA ermöglicht die Proteinexpression von Hunderten von Proben auf Nitrozellulose Folien gedruckt, um gleichzeitig abgefragt werden, mit fluoreszenzmarkierten Antikörpern. Diese Technik angewendet worden ist, um die Wirkung der medikamentösen Behandlung Heterogenität innerhalb klarzelligen Nierenkarzinom studieren.

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Cancer Biology Ausgabe 71 Bioengineering Medizin Biomedizintechnik Zellbiologie Molekularbiologie Genetik Pathologie Onkologie Proteine Früherkennung von Krebs Translational Medical Research RPPA RCC Heterogenität Proteomics Tumor Grade intertumoral Tumor metastasierendem Karzinom Nierenkrebs klarzelligen Nierenzellkarzinom Krebs Assay
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