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JoVE Journal Bioengineering
Test di suscettibilità agli antibiotici indotti dallo stress su un chip
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Test di suscettibilità agli antibiotici indotti dallo stress su un chip

Article DOI: 10.3791/50828-v • 12:41 min • January 8th, 2014
January 8th, 2014 •
1, 1, 2, 1,3, 1,4
1Fraunhofer USA Center for Manufacturing Innovation, 2Division of Infectious Diseases, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 3Department of Mechanical Engineering, Boston University, 4Department of Biomedical Engineering, Boston University

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Abbiamo sviluppato una piattaforma microfluidica per test di suscettibilità agli antibiotici rapidi. Il fluido viene passato ad alta velocità sui batteri immobilizzati sul fondo di un canale microfluidico. In presenza di stress e antibiotici, i ceppi sensibili di batteri muoiono rapidamente. Tuttavia, i batteri resistenti possono sopravvivere a queste condizioni stressanti.

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Bioingegneria Numero 83 antibiotico suscettibilità resistenza microfluidica microscopia rapido test stress batteri fluorescenza
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