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Cancro ipossia stampato in cellule 3D su chip per ricapitolare la progressione patologica del cancro solido
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1Department of Mechanical Engineering,Pohang University of Science and Technology (POSTECH), 2Department of Creative IT Engineering,Pohang University of Science and Technology (POSTECH), 3Department of Rural and Biosystems Engineering, College of Agriculture and Life Sciences,Chonnam National University
Chapters
- 00:05Introduction
- 00:56Collagen Pre-Gel Solution Preparation
- 01:471% Neutralized Collagen Pre-Gel Solution pH Adjustment
- 03:12Gas-Permeable Barrier 3D Printing
- 04:20Polydimethylsiloxane (PDMS) Barrier Casting
- 05:291% Neutralized Collagen Pre-Gel Solution Cell Mixing
- 06:19Cancer-Stroma Concentric Ring 3D Cell Printing
- 07:39Hypoxic Cancer-on-a-Chip Maintenance
- 08:11Results: Representative Solid Pathologic Cancer Progression on a 3D Cell-Printed Hypoxic Cancer-on-a-Chip
- 10:06Conclusion
L'ipossia è un segno distintivo del microambiente tumorale e svolge un ruolo cruciale nella progressione del cancro. Questo articolo descrive il processo di fabbricazione di un cancro ipossico su chip basato sulla tecnologia di stampa cellulare 3D per ricapitolare una patologia del cancro correlata all'ipossia.
