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Profilering af østrogen-regulerede MicroRNA i brystkræftceller

Article DOI: 10.3791/51285 • 16:24 min
February 21st, 2014 •
1, 1
1Center for Nuclear Receptors and Cell Signaling, Department of Biology and Biochemistry, University of Houston

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February 21st, 2014

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Molekylær signalering gennem både østrogen og microRNA'er er kritiske i brystkræft udvikling og vækst. Østrogen aktiverer østrogenreceptorer, som transkriptionsfaktorer. Mange transkriptionsfaktorer kan regulere ekspression af microRNA, og østrogen-regulerede microRNA kan profileres ved hjælp af forskellige storstilede teknikker.

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