JoVE
JoVE
Faculty Resource Center
Research
Behavior
Biochemistry
Biology
Bioengineering
Cancer Research
Chemistry
Developmental Biology
Engineering
Environment
Genetics
Immunology and Infection
Medicine
Neuroscience
JoVE Journal
JoVE Encyclopedia of Experiments
JoVE Chrome Extension
Education
Biology
Chemistry
Clinical
Engineering
Environmental Sciences
Pharmacology
Physics
Psychology
Statistics
JoVE Core
JoVE Science Education
JoVE Lab Manual
JoVE Quiz
JoVE Business
Videos Mapped to your Course
Authors
Librarians
High Schools
About
Sign-In
Sign In
Contact Us
Research
JoVE Journal
JoVE Encyclopedia of Experiments
Education
JoVE Core
JoVE Science Education
JoVE Lab Manual
High Schools
EN
EN - English
CN - 中文
DE - Deutsch
ES - Español
KR - 한국어
IT - Italiano
FR - Français
PT - Português
EN
EN - English
CN - 中文
DE - Deutsch
ES - Español
KR - 한국어
IT - Italiano
FR - Français
PT - Português
Close
Research
Behavior
Biochemistry
Bioengineering
Biology
Cancer Research
Chemistry
Developmental Biology
Engineering
Environment
Genetics
Immunology and Infection
Medicine
Neuroscience
Products
JoVE Journal
JoVE Encyclopedia of Experiments
Education
Biology
Chemistry
Clinical
Engineering
Environmental Sciences
Pharmacology
Physics
Psychology
Statistics
Products
JoVE Core
JoVE Science Education
JoVE Lab Manual
JoVE Quiz
JoVE Business
Videos Mapped to Your Course
Teacher Resources
Get in Touch
Instant Trial
Log In
EN
EN - English
CN - 中文
DE - Deutsch
ES - Español
KR - 한국어
IT - Italiano
FR - Français
PT - Português
Journal
/
Behavior
/
评估在功能性能<em> MDX</em>小鼠模型
JoVE Journal
Behavior
A subscription to JoVE is required to view this content.
Sign in or start your free trial.
JoVE Journal
Behavior
Assessing Functional Performance in the
Mdx
Mouse Model
Please note that all translations are automatically generated.
Click here for the English version.
评估在功能性能<em> MDX</em>小鼠模型
DOI:
10.3791/51303-v
•
10:32 min
•
March 27, 2014
•
Annemieke Aartsma-Rus
,
Maaike van Putten
1
Department of Human Genetics
,
Leiden University Medical Center
Chapters
00:05
Title
02:39
Hanging Tests: Two Limbs
04:07
Hanging Tests: Four Limbs
05:00
Rotarod Running
06:16
Treadmill Exercise
06:50
Results: Functional Performance of
Mdx
and Wild Type Mice
09:49
Conclusion
10:31
Forelimb Grip Strength Test
Summary
Automatic Translation
English (Original)
العربية (Arabic)
中文 (Chinese)
Nederlands (Dutch)
français (French)
Deutsch (German)
עברית (Hebrew)
italiano (Italian)
日本語 (Japanese)
한국어 (Korean)
português (Portuguese)
русский (Russian)
español (Spanish)
Türkçe (Turkish)
Automatic Translation
在对神经肌肉疾病的临床试验的主要终点是普遍改善肌肉功能。因此,评估潜在的治疗化合物对肌肉性能在小鼠模型中的临床前的效果是非常重要的。我们在这里介绍几种功能测试,以解决这一问题。
Tags
Duchenne Muscular Dystrophy
DMD
Mdx Mouse Model
Muscle Function
Muscle Strength
Muscle Coordination
Functional Tests
Grip Strength
Hanging Test
Rotarod
Treadmill Running
Pre-clinical Assessment
Therapeutic Interventions
Article
Embed
ADD TO PLAYLIST
Usage Statistics
Related Videos
同时头皮脑电图(EEG),肌电图(EMG)和全身分部惯性录制多模态神经解码
针对调查中的认知控制网络与关联维度变化卡片分类性能的功能连通性年龄相关性差异的方法
情绪Stroop任务:评估下暴露的认知表现的情感内容
鼠类精神运动警觉测试(rPVT):一个在大鼠和小鼠的神经行为评估性能的方法
使用径向水痕迷宫评估外伤性脑损伤小鼠模型中的空间记忆障碍
小鼠主动和被动驯服的测定
使用五分钟言语样本程序评估家长对孩子的简短叙述的一致性
评估合作伙伴对大鼠电机性能速度和准确性的影响的任务
训练犬为觉醒,无节制的功能磁共振成像
现实世界中的人类昼夜Phenotyping和二年性能测试
Read Article