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Fænotype Mouse lungefunktion<em> In Vivo</em> Med Lung diffuserende Capacity
JoVE Journal
Biology
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JoVE Journal Biology
Phenotyping Mouse Pulmonary Function In Vivo with the Lung Diffusing Capacity

Fænotype Mouse lungefunktion<em> In Vivo</em> Med Lung diffuserende Capacity

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07:13 min

January 06, 2015

DOI:

07:13 min
January 06, 2015

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Summary

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We describe a means to quickly and simply measure the lung diffusing capacity in mice and show that it is sufficiently sensitive to phenotype changes in multiple common lung pathologies. This metric thus brings direct translational relevance to the mouse models, since diffusing capacity is also easily measured in humans.

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