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Journal / Neuroscience / Modellering Snel-scannen Cyclische Voltammetrie…
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Neuroscience

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JoVE Journal Neuroscience
Modellering Snel-scannen Cyclische Voltammetrie Gegevens van Elektrisch Gestimuleerde Dopamine Neurotransmissie Gegevens Met behulp van QNsim1.0
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Modellering Snel-scannen Cyclische Voltammetrie Gegevens van Elektrisch Gestimuleerde Dopamine Neurotransmissie Gegevens Met behulp van QNsim1.0

Article DOI: 10.3791/55595-v • 07:41 min • June 5th, 2017
June 5th, 2017 •
1,2,3, 2, 2,4, 1,2,3
1Center for Neuroscience, University of Pittsburgh, 2Department of Physical Medicine & Rehabilitation, University of Pittsburgh, School of Medicine, 3Safar Center for Resuscitation Research, University of Pittsburgh, 4Department of Biological Sciences, Mellon College of Science, Carnegie Mellon University

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Snelle-scan cyclische voltammetrie kan in vivo dopamine neurotransmissie in de context van drugs, ziekte en andere experimentele manipulaties monitoren. Dit werk beschrijft de implementatie van QNsim1.0, een software voor het modelleren van elektrisch gestimuleerde dopamine responsen volgens het kwantitatieve neurobiologische model om schattingen van dopamine release en reuptake dynamics te kwantificeren.

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Neuroscience dopamine snelle scan cyclische voltammetrie synaptische transmissie psychostimulanten methylphenidaat kwantitatief neurobiologisch model
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