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JoVE Journal Genetics
Cartographie génomique des interactions protéine-ADN avec ChEC-seq in
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Cartographie génomique des interactions protéine-ADN avec ChEC-seq in

Article DOI: 10.3791/55836-v • 10:43 min • June 3rd, 2017
June 3rd, 2017 •
1, 2
1Basic Sciences Division, Fred Hutchinson Cancer Research Center, 2Department of Biology, Indiana University

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Nous décrivons le clivage endogène de la chromatine couplé au séquençage à haut débit (ChEC-seq), une méthode orthogonale à l'immunoprécipitation à la chromatine (ChIP) pour cartographier les sites de liaison des protéines à l'échelle du génome avec des protéines de fusion à la nucléase micrococcie (MNase).

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Genetics ChEC-seq ChIP-seq transcription génome-large Médiateur,
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