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Journal / Genetics / 高分辨率融合PCR用于补体受体1长度多态性基因分型：阿尔茨海默病基因易感性评估的创新工具…
JoVE Journal
Genetics

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JoVE Journal Genetics
高分辨率融合PCR用于补体受体1长度多态性基因分型：阿尔茨海默病基因易感性评估的创新工具
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高分辨率融合PCR用于补体受体1长度多态性基因分型：阿尔茨海默病基因易感性评估的创新工具

Article DOI: 10.3791/56012-v • 07:26 min • July 18th, 2017
July 18th, 2017 •
1,2, 1,2, 1,2, 1,2, 3,4
1Department of Immunology, Reims University Hospitals, Robert Debré Hospital, 2Faculty of Medicine, LRN EA 4682, University of Reims Champagne-Ardenne, 3Department of Internal Medicine and Geriatrics, Reims University Hospitals, Maison Blanche Hospital, 4Faculty of Medicine, EA 3797, University of Reims Champagne-Ardenne

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在这里，我们描述了一种用于确定补体受体1（CR1）长度多态性的创新方法，用于多种应用，特别是对诸如阿尔茨海默病（AD）等疾病的易感性的评估。这种方法可能有助于更好地了解CR1同种型在AD发病机制中的作用。

Tags

遗传学，第125期，CR1，CD35，补体C3b / C4b受体，CR1长度多态性，补体，阿尔茨海默病，分子生物学，神经科学，系统性红斑狼疮，遗传风险
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