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In Vivo Evaluation of Fracture Callus Development During Bone Healing in Mice Using an MRI-compatible Osteosynthesis Device for the Mouse Femur
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In Vivo Evaluation of Fracture Callus Development During Bone Healing in Mice Using an MRI-compatible Osteosynthesis Device for the Mouse Femur

In Vivo Evaluation of Fracture Callus Development During Bone Healing in Mice Using an MRI-compatible Osteosynthesis Device for the Mouse Femur

DOI:
10.3791/56679-v

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07:33 min

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November 14, 2017

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, , , , , , ,
1Institute of Orthopedic Research and Biomechanics,University Medical Center Ulm, 2RISystem, 3Core Facility Small Animal MRI,University Medical Center Ulm, 4Department of Traumatology, Hand-, Plastic-, and Reconstructive Surgery,University Medical Center Ulm

Chapters

  • 00:05Title
  • 00:52External Fixator Application
  • 03:26Magnetic Resonance Imaging (MRI) and Analysis
  • 05:39Results: Representative MRI and 3D Imaging Analyses of Fracture Callus development
  • 06:57Conclusion

Summary

Automatic Translation

Automatic Translation

The evaluation of tissue development in the fracture callus during endochondral bone healing is essential to monitor the healing process. Here, we report the use of a magnetic resonance imaging (MRI)-compatible external fixator for the mouse femur to allow MRI scans during bone regeneration in mice.

Tags

Keywords: MRIFracture CallusBone HealingMouse FemurExternal FixatorOsteotomyLongitudinal EvaluationIn VivoStandardized Fracture Model

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