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CMAP Scan MUNE (MScan) – A Novel Motor Unit Number Estimation (MUNE) Method
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JoVE Journal Neuroscience
CMAP Scan MUNE (MScan) – A Novel Motor Unit Number Estimation (MUNE) Method

CMAP Scan MUNE (MScan) – A Novel Motor Unit Number Estimation (MUNE) Method

DOI:
10.3791/56805-v

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08:25 min

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June 07, 2018

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, ,
1Department of Clinical Neurophysiology,Aarhus University Hospital, 2Institute of Neurology,Queen Square House

Chapters

  • 00:05Title
  • 00:45Subject Preparation
  • 01:49Recording the CMAP Scan
  • 04:47Fitting the Model to the CMAP Scan
  • 06:32Results: CMAP Scan MUNE Differentiates ALS Patients from Healthy Controls
  • 07:33Conclusion

Summary

Automatic Translation

Automatic Translation

This protocol describes a new method to estimate the number of functioning motor units in a muscle, by fitting a model to a detailed stimulus-response curve of the compound muscle action potential. It is quick and easy to perform and analyze and has excellent reproducibility.

Tags

Keywords: CMAP ScanMUNEMotor Unit Number EstimationMScanNon-invasiveStimulus-response CurveMotor Nerve Excitability TestsAbductor Pollicis BrevisMedian NerveEMGElectrode Placement

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