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Journal / Immunology and Infection / Medição de deformabilidade e heterogeneidade de…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Medição de deformabilidade e heterogeneidade de glóbulos vermelhos no sangue por Ektacytometry
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Medição de deformabilidade e heterogeneidade de glóbulos vermelhos no sangue por Ektacytometry

Article DOI: 10.3791/56910-v • 09:12 min • January 12th, 2018
January 12th, 2018 •
*1, *2, 2, 3, 4, 4, 1,5, 6, 3, 2
1Department of Pediatrics, Saint Louis University School of Medicine, 2Molecular and Clinical Nutrition Section, Digestive Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, 3Molecular and Clinical Hematology Branch, National Institute of Diabetes and Digestive and Kidney Diseases, 4Sickle Cell Branch, National Heart, Lung and Blood Institute, National Institutes of Health, 5Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, 6Red Cell Physiology Laboratory, New York Blood Center
* These authors contributed equally

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Aqui nós apresentamos técnicas para medir a deformabilidade eritrócitos e heterogeneidade celular por ektacytometry. Estas técnicas são aplicáveis às investigações gerais de deformabilidade eritrócitos e investigações específicas de doenças do sangue caracterizadas pela presença de eritrócitos rígidas e deformáveis em circulação, tais como anemia falciforme.

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Imunologia questão 131 hemoglobina Fetal ektacytometry gradiente osmótico eritrócitos deformabilidade anemia falciforme distorção de difração
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