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测量任意数量药物协同作用的对角方法
JoVE Journal
Biology
This content is Free Access.
JoVE Journal
Biology
Diagonal Method to Measure Synergy Among Any Number of Drugs
Please note that all translations are automatically generated.
Click here for the English version.
测量任意数量药物协同作用的对角方法
DOI:
10.3791/57713-v
•
12:08 min
•
June 21, 2018
•
Melike Cokol-Cakmak
,
Feray Bakan
,
Selim Cetiner
,
Murat Cokol
2,3
1
Faculty of Engineering and Natural Sciences
,
Sabanci University
,
2
Nanotechnology Research and Application Center
,
Sabanci University
,
3
Laboratory of Systems Pharmacology
,
Harvard Medical School
Chapters
00:04
Title
00:28
Serial Dilution Dose-Response Experiment
04:29
Linear Dilution Dose-Response Experiment
07:21
Diagonal Drug Interaction Experiment and Interaction Scores
09:51
Results: Analysis of the Diagonal Drug Interaction Experiment
11:11
Conclusion
Summary
Automatic Translation
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Automatic Translation
在本协议中, 我们描述了如何使卢安克加的药物相互作用测量成对和三路药物组合。
Tags
Diagonal Method
Synergy
Multiple Drugs
Systems Biology
Antibiotic Aliquots
Bacterial Culture
Serial Dilutions
LB Media
DMSO
LEV
NAL
PNG
OD600
Dose-response Experiment
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