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JoVE Journal Behavior
En Microphysiologic plattform for menneskelig fett
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En Microphysiologic plattform for menneskelig fett: klemt hvit fettvev

Article DOI: 10.3791/57909-v • 08:14 min • August 15th, 2018
August 15th, 2018 •
1, 2, 2, 2
1Department of Pharmacology, Louisiana State University Health Sciences Center, 2Department of Surgery, Louisiana State University Health Sciences Center

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Hvit fettvev (WAT) har kritiske mangler i sin nåværende primære kultur modeller, hindre farmakologiske utvikling og metabolske studier. Her presenterer vi en protokoll for å produsere en adipose microphysiological system av sandwiching WAT mellom ark stromal celler. Denne konstruksjonen gir en stabil og tilpasses plattform for primære WAT kultur.

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Atferd problemet 138 fettvev adipocytter fedme microphysiological systemer organer på chips narkotikarelaterte screening narkotika utvikling miljømessige toksisitet primære kultur diabetes metabolisme
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