Analyzing Spatial Learning and Prosocial Behavior in Mice Using the Barnes Maze and Damsel-in-Distress Paradigms

James Ingersoll; Michael Moody; Robert Holland; Wesley Kuegler; Charles Murrah Jr.; John Winslow; Neal Reynolds; Nathaniel Lloyd; Brian Dugan; Madalyn Hammock; Katherine Houl&#233;; Erin Clabough

doi:10.3791/58008

Journal

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Behavior

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Analyzing Spatial Learning and Prosocial Behavior in Mice Using the Barnes Maze and Damsel-in-Distress Paradigms

JoVE Journal
Behavior

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JoVE Journal Behavior

Analyzing Spatial Learning and Prosocial Behavior in Mice Using the Barnes Maze and Damsel-in-Distress Paradigms

14,011 Views

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08:00 min

•

November 17, 2018

DOI:

10.3791/58008-v

DOI:

10.3791/58008-v

•

08:00 min

November 17, 2018

•

13968 Views

James Ingersoll¹, Michael Moody¹, Robert Holland¹, Wesley Kuegler¹, Charles Murrah Jr.¹, John Winslow¹, Neal Reynolds¹, Nathaniel Lloyd¹, Brian Dugan¹, Madalyn Hammock¹, Katherine Houlé², Erin Clabough¹

¹Department of Biology,Hampden-Sydney College ²College of Medicine at the Medical University of South Carolina,College of South Carolina

Summary

This protocol measures spatial learning and memory using the Barnes maze. A novel Damsel-in-Distress paradigm is used to assess locomotor activity and prosocial behavior in mice.

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Spatial Learning Prosocial Behavior Barnes Maze Damsel-in-Distress Paradigms Behavioral Neuroscience Genetic Mutations Environmental Variables Social Behaviors Spatial Memories Mouse Model Empathy Measure Maze Testing Procedure Training Test Acclimation Video Recording Search Strategies Target Hole Ultrasonic Noise Animal Movement Tracking

Analyzing Spatial Learning and Prosocial Behavior in Mice Using the Barnes Maze and Damsel-in-Distress Paradigms

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