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Analyzing Spatial Learning and Prosocial Behavior in Mice Using the Barnes Maze and Damsel-in-Distress Paradigms
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Behavior
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JoVE Journal Behavior
Analyzing Spatial Learning and Prosocial Behavior in Mice Using the Barnes Maze and Damsel-in-Distress Paradigms

Analyzing Spatial Learning and Prosocial Behavior in Mice Using the Barnes Maze and Damsel-in-Distress Paradigms

DOI:
10.3791/58008-v

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08:00 min

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November 17, 2018

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, , , , , , , , , , ,
1Department of Biology,Hampden-Sydney College, 2College of Medicine at the Medical University of South Carolina,College of South Carolina

Chapters

  • 00:04Title
  • 00:42Barnes Maze Testing Procedure and Data Analysis
  • 03:08Damsel-in-Distress Testing: Exploratory Behavior and Social Responsiveness Measures and Data Analysis
  • 06:11Results: Representative Murine Spatial Learning and Prosocial Behavior Analyses
  • 07:32Conclusion

Summary

Automatic Translation

Automatic Translation

This protocol measures spatial learning and memory using the Barnes maze. A novel Damsel-in-Distress paradigm is used to assess locomotor activity and prosocial behavior in mice.

Tags

Keywords: Spatial LearningProsocial BehaviorBarnes MazeDamsel-in-Distress ParadigmsBehavioral NeuroscienceGenetic MutationsEnvironmental VariablesSocial BehaviorsSpatial MemoriesMouse ModelEmpathy MeasureMaze Testing ProcedureTraining TestAcclimationVideo RecordingSearch StrategiesTarget HoleUltrasonic NoiseAnimal Movement Tracking

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