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JoVE Journal
Cancer Research

This content is Open Access.

JoVE Journal Cancer Research
Preparation of Exosomes for siRNA Delivery to Cancer Cells
 

Preparation of Exosomes for siRNA Delivery to Cancer Cells

Article doi: 10.3791/58814
December 5th, 2018 •
*1, *1, 1
1Institute of Pharmaceutical Science, King's College London
* These authors contributed equally

Summary
Automatic Translation
December 5th, 2018

An exosome is a new generation of drug delivery carriers. We established an exosome isolation protocol with high yield and purity for siRNA delivery. We also encapsulated fluorescently labelled non-specific siRNA into exosomes and investigated the cellular uptake of siRNA-loaded exosomes in cancer cells.

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