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Preparation of Exosomes for siRNA Delivery to Cancer Cells
Preparation of Exosomes for siRNA Delivery to Cancer Cells
JoVE Journal
Cancer Research
This content is Free Access.
JoVE Journal Cancer Research
Preparation of Exosomes for siRNA Delivery to Cancer Cells

Preparation of Exosomes for siRNA Delivery to Cancer Cells

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09:59 min

December 05, 2018

DOI:

09:59 min
December 05, 2018

24950 Views
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Summary

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An exosome is a new generation of drug delivery carriers. We established an exosome isolation protocol with high yield and purity for siRNA delivery. We also encapsulated fluorescently labelled non-specific siRNA into exosomes and investigated the cellular uptake of siRNA-loaded exosomes in cancer cells.

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