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JoVE Journal
Cancer Research

This content is Open Access.

Preparation of Exosomes for siRNA Delivery to Cancer Cells
 

Preparation of Exosomes for siRNA Delivery to Cancer Cells

Article DOI: 10.3791/58814-v
December 5th, 2018

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Summary December 5th, 2018

An exosome is a new generation of drug delivery carriers. We established an exosome isolation protocol with high yield and purity for siRNA delivery. We also encapsulated fluorescently labelled non-specific siRNA into exosomes and investigated the cellular uptake of siRNA-loaded exosomes in cancer cells.

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