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Immunology and Infection

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Induction of Mouse Lung Injury by Endotracheal Injection of Bleomycin
 

Induction of Mouse Lung Injury by Endotracheal Injection of Bleomycin

Article doi: 10.3791/58922
April 30th, 2019

Summary April 30th, 2019

Here we present an effective method to investigate the antifibrotic activity of intravenously infused human mesenchymal stromal cells obtained from the whole umbilical cord following the induction of lung injury by an endotracheal injection of bleomycin in C57BL/6 mice. This protocol can be easily extended to the preclinical testing of other therapeutics.

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