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JoVE Journal
Immunology and Infection

This content is Open Access.

Quantification of Atherosclerosis in Mice

Quantification of Atherosclerosis in Mice

Article DOI: 10.3791/59828-v
June 12th, 2019


Summary June 12th, 2019

Murine models of atherosclerosis are useful tools to investigate pathogenic pathways on a molecular level, but require standardized quantification of lesion development. This protocol describes an optimized method to determine lesion size in the major arterial vessels including the aortic root, aortic arch, and brachiocephalic artery.


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