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Fremstilling af SNS Cobalt (II) Pincer Model komplekser af leveralkohol Dehydrogenase
JoVE Journal
Chemistry
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JoVE Journal Chemistry
Preparation of SNS Cobalt(II) Pincer Model Complexes of Liver Alcohol Dehydrogenase
DOI:

06:31 min

March 19, 2020

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Chapters

  • 00:04Introduction
  • 00:52Chloro-(n3-S,S,N)-[2,6-bis(N-isopropyl-N -methyleneimidazole-2-thione)pyridine]cobalt(II)tetrachlorocobaltate [4] Synthesis
  • 01:42Chloro-(n3-S,S,N)-[2,6-bis(N-isopropyl-N -methyleneimidazole-2-thione)pyridine]cobalt(II)tetrachlorocobaltate [4] Recrystallization
  • 02:34Chloro-(n3-S,S,N)-[2,6-bis(N-isopropyl-N -methylenetriazole-2-thione)pyridine]cobalt(II)tetrachlorocobaltate [5] Synthesis
  • 03:22Chloro-(n3-S,S,N)-[2,6-bis(N-isopropyl-N’-methylenetriazole-2-thione)pyridine]cobalt(II) tetrachlorocobaltate [5] Recrystallization
  • 04:28Results: Representative Liver Alcohol Dehydrogenase Complex Analyses
  • 05:41Conclusion

Summary

Automatic Translation

Udarbejdelsen af SNS pincer cobalt (II) model komplekser af leveralkohol dehydrogenase præsenteres her. Komplekserne kan fremstilles ved at reagere på ligandforløberen med CoCl2·6H2O og kan derefter omkrystalliseres ved at tillade diethylether langsomt at sprede sig til en acetonitrilopløsning, der indeholder koboltkomplekset.

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