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Journal / Medicine / Model af iskæmisk hjertesygdom og video-baseret…
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Medicine

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JoVE Journal Medicine
Model af iskæmisk hjertesygdom og video-baseret sammenligning af Cardiomyocyte sammentrækning ved hjælp af hiPSC-afledte kardiomyocytter
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Model af iskæmisk hjertesygdom og video-baseret sammenligning af Cardiomyocyte sammentrækning ved hjælp af hiPSC-afledte kardiomyocytter

Article DOI: 10.3791/61104-v • 05:06 min • May 5th, 2020
May 5th, 2020 •
*1, *1, *1, 1, 2, 1, 1
1Department of Cardiovascular Physiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 2Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University
* These authors contributed equally

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Vi præsenterer en model af iskæmisk hjertesygdom ved hjælp af kardiomyocytter stammer fra humane inducerede pluripotente stamceller, sammen med en metode til kvantitativ vurdering af vævsskader forårsaget af iskæmi. Denne model kan give en nyttig platform for narkotika screening og yderligere forskning i iskæmisk hjertesygdom.

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Medicin Iskæmisk hjertesygdom hypoxi Myokardieinfarkt Human induceret pluripotente stamceller cellulære differentiering Kardiomyocytter
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