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En Syngeneic Murine Model af endometriose ved hjælp af naturligt cykling Mus
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En Syngeneic Murine Model af endometriose ved hjælp af naturligt cykling Mus

Article DOI: 10.3791/61960-v • 07:12 min • November 24th, 2020
November 24th, 2020 •
*1, *2, 3, 1, 1, 4, 4, 1,5
1Cardiovascular and Metabolic Sciences, Lerner Research Institute; Women’s Health Institute, Cleveland Clinic, 2Women’s Health Institute, Cleveland Clinic, 3Department of Obstetrics and Gynecology, 983255 Nebraska Medical Center, University of Nebraska Medical Center, 4Anatomic Pathology, Cleveland Clinic, 5Gynecologic Oncology, Women’s Health Institute and Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Cleveland Clinic
* These authors contributed equally

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Mange gnavermodeller af endometriose er begrænset af teknisk kompleksitet, reproducerbarhed og/eller behov for immunkompromitterede dyr eller specielle reportermus. Vi præsenterer et forenklet system af læsionsinduktion ved hjælp af enhver eksperimentel mus med et uafhængigt verificerbart, objektivt scoringssystem og uden krav om ovariektomi eller overlevelseskirurgi.

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Medicin endometriose dyremodel syngeneic murine retrograd menstruation endometrium
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