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Un modelo murino singénico de endometriosis utilizando ratones de ciclo natural
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Un modelo murino singénico de endometriosis utilizando ratones de ciclo natural

Article DOI: 10.3791/61960-v • 07:12 min • November 24th, 2020
November 24th, 2020 •
*1, *2, 3, 1, 1, 4, 4, 1,5
1Cardiovascular and Metabolic Sciences, Lerner Research Institute; Women’s Health Institute, Cleveland Clinic, 2Women’s Health Institute, Cleveland Clinic, 3Department of Obstetrics and Gynecology, 983255 Nebraska Medical Center, University of Nebraska Medical Center, 4Anatomic Pathology, Cleveland Clinic, 5Gynecologic Oncology, Women’s Health Institute and Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Cleveland Clinic
* These authors contributed equally

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Muchos modelos de roedores de endometriosis están limitados por la complejidad técnica, la reproducibilidad y / o la necesidad de animales inmunocomprometidos o ratones reporteros especiales. Presentamos un sistema simplificado de inducción de lesiones utilizando cualquier ratón experimental con un sistema de puntuación objetivo verificable de forma independiente y sin necesidad de ovariectomía o cirugía de supervivencia.

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Medicina Número 165 endometriosis modelo animal singénica murina menstruación retrógrada endometrio
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