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Kvantitativa metoder för att studera protein arginin metyltransferas 1-9 Aktivitet i celler
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Kvantitativa metoder för att studera protein arginin metyltransferas 1-9 Aktivitet i celler

Article DOI: 10.3791/62418-v • 08:11 min • August 7th, 2021
August 7th, 2021 •
1, 1, 1,2
1Structural Genomics Consortium, University of Toronto, 2Department of Pharmacology and Toxicology, University of Toronto

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Dessa protokoll ger den metod som används för att bedöma enzymatisk aktivitet hos enskilda medlemmar av proteinet argininmetyltransferas (PRMT) i celler. Detaljerade riktlinjer för bedömning av PRMT verksamhet med hjälp av endogena och exogena biomarkörer, metyl-arginin erkänna antikroppar och inhibitor verktyg föreningar beskrivs.

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Biologi nummer 174
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