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JoVE Journal Bioengineering
Modulerende form af polyesterbaserede polymersomer ved hjælp af osmotisk tryk
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Modulerende form af polyesterbaserede polymersomer ved hjælp af osmotisk tryk

Article DOI: 10.3791/62548-v • 06:01 min • April 21st, 2021
April 21st, 2021 •
1, 2, 1,3
1Department of Chemical and Biomolecular Engineering, Clemson University, 2Department of Biological Sciences, Clemson University, 3Department of Bioengineering, Clemson University

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Polymersomer er selvsamlede polymere vesikler, der er dannet i sfæriske former for at minimere Gibb's Free Energy. I tilfælde af levering af lægemidler er mere aflange strukturer gavnlige. Denne protokol etablerer metoder til at skabe mere stang-lignende polymersomer, med aflange højde-bredde-forhold, ved hjælp af salt til at fremkalde osmotisk tryk og reducere interne vesikel mængder.

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Bioengineering polymersome nanomedicin formmodulation nanoteknologi lægemiddellevering polyestere
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