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Journal / Cancer Research / Reconstrueer humaan retinoblastoom in vitro
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JoVE Journal Cancer Research
Reconstrueer humaan retinoblastoom in vitro
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Reconstrueer humaan retinoblastoom in vitro

Article DOI: 10.3791/62629-v • 06:52 min • October 11th, 2022
October 11th, 2022 •
1, 1
1Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Science Key Laboratory

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We beschrijven een methode voor het genereren van humaan retinoblastoom (RB) door biallelische RB1-mutaties in menselijke embryonale stamcellen (hESC) te introduceren. RB-cellijnen kunnen ook met succes worden gekweekt met behulp van de geïsoleerde RB in een schaal.

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Kankeronderzoek Nummer 188
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