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Cancer Research

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JoVE Journal Cancer Research
Kultur av blåscancerorganoider som precisionsmedicinska verktyg
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Kultur av blåscancerorganoider som precisionsmedicinska verktyg

Article DOI: 10.3791/63192-v • 08:39 min • December 28th, 2021
December 28th, 2021 •
1,2,3,4, 1,2,3,4,5, 1,4, 1,4,5, 1,2, 1,2, 1,2,4, 1,2,3,4, 1,2,3, 1,2, 1,2, 1,2,3,4, *1,2,3,4,5, *1,2,3,4
1School of Biomedical Sciences, Faculty of Health, Queensland University of Technology (QUT) at Translational Research Institute, 2Queensland Bladder Cancer Initiative (QBCI), 3Centre for Personalised Analysis of Cancers (CPAC), 4Australian Prostate Cancer Research Centre - Queensland, 5Department of Urology, Princess Alexandra Hospital
* These authors contributed equally

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Patient-härledda organoider (PDO) är ett kraftfullt verktyg i translationell cancerforskning, vilket återspeglar både den genetiska och fenotypiska heterogeniteten hos sjukdomen och svaret på personliga anti-cancerterapier. Här beskrivs ett konsoliderat protokoll för att generera humana primära blåscancer-SUB som förberedelse för utvärdering av fenotypiska analyser och läkemedelssvar.

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Cancerforskning utgåva 178
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