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JoVE Journal
Bioengineering
Author Produced

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创建膝关节芯片,用于关节疾病建模和药物测试
 
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创建膝关节芯片,用于关节疾病建模和药物测试

Article DOI: 10.3791/64186-v 12:44 min January 27th, 2023
January 27th, 2023

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Summary

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我们提供了从人间充质干细胞生成四种类型的组织的详细方法,这些组织用于概括人膝关节中的软骨、骨骼、脂肪垫和滑膜。这四个组织被集成到一个定制的生物反应器中,并通过微流体连接,从而产生一个膝关节芯片。

Tags

生物工程,第191期,骨关节炎,组织芯片,疾病修饰性骨关节炎药物,微生理系统
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