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JoVE Journal Immunology and Infection
Kontaktoverfølsomhed som en Murine-model af allergisk kontaktdermatitis
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Kontaktoverfølsomhed som en Murine-model af allergisk kontaktdermatitis

Article DOI: 10.3791/64329-v • 08:25 min • September 26th, 2022
September 26th, 2022 •
1, 2, 1, 3
1Department of Clinical Immunology, Wroclaw Medical University, 2Department of Medical Physiology, Chair of Biomedical Sciences, Institute of Physiotherapy, Faculty of Health Sciences, Jagiellonian University Medical College, 3Chair of Biomedical Sciences, Faculty of Health Sciences, Jagiellonian University Medical College

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Kontaktoverfølsomhed (CHS) er en murin eksperimentel model af allergisk kontaktdermatitis (ACD). CHS er baseret på sensibilisering med reaktiv hapten ved at male den barberede hud i brystet og maven med en efterfølgende ørehududfordring med en fortyndet hapten, hvilket forårsager en hævelsesreaktion, der vurderes på forskellige måder.

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Immunologi og infektion udgave 187 Murine-model allergisk kontaktdermatitis (ACD) kontaktoverfølsomhed (CHS) hævelse i øret vaskulær permeabilitet myeloperoxidase (MPO) cytokiner 2,4,6-trinitrochlorbenzen (TNCB) hapten
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