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Una tecnica modificata per la costrizione aortica trasversale nei topi
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Una tecnica modificata per la costrizione aortica trasversale nei topi

Article DOI: 10.3791/64386-v • 04:52 min • August 18th, 2022
August 18th, 2022 •
*1,2, *1,2, *1,2, 1,2
1Division of Cardiology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 2Hubei Key Laboratory of Genetics and Molecular Mechanism of Cardiological Disorders, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
* These authors contributed equally

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Il presente protocollo descrive una tecnica modificata e semplificata con una procedura di costrizione aortica trasversale mini-invasiva (TAC) utilizzando un divaricatore autocostruito. Questa procedura può essere condotta senza un ventilatore o un microscopio e introduce un sovraccarico di pressione, portando infine a ipertrofia cardiaca o insufficienza cardiaca.

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Biologia Numero 186
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