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JoVE Journal Bioengineering
Microengenharia 3D Colágeno Hidrogéis com Alinhamento de Fibras de Longo Alcance
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Microengenharia 3D Colágeno Hidrogéis com Alinhamento de Fibras de Longo Alcance

Article DOI: 10.3791/64457-v • 07:12 min • September 7th, 2022
September 7th, 2022 •
1, 1, 1, 1, 1, 1, 1, 1
1Department of Biomedical Engineering, Kate Gleason College of Engineering, Rochester Institute of Technology

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Este protocolo demonstra o uso de um canal microfluídico com geometria variável ao longo da direção do fluxo de fluido para gerar deformação extensional (alongamento) para alinhar as fibras em um hidrogel de colágeno 3D (<250 μm de espessura). O alinhamento resultante se estende por vários milímetros e é influenciado pela taxa de deformação extensional.

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