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Journal / Cancer Research / Glioblastoma multiforme'un Translasyonel…
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JoVE Journal Cancer Research
Glioblastoma multiforme'un Translasyonel Ortotopik Modelleri
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Glioblastoma multiforme'un Translasyonel Ortotopik Modelleri

Article DOI: 10.3791/64482-v • 07:37 min • February 17th, 2023
February 17th, 2023 •
1, 1, 1
1Center for Advanced Preclinical Research, Frederick National Laboratory for Cancer Research, National Cancer Institute

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Burada, genetiği değiştirilmiş fare modeli tümörlerinden türetilen hücrelerin intrakraniyal enjeksiyonu ile kurulan GBM için klinik öncesi bir ortotopik fare modelini tarif ediyoruz. Bu model, insan GBM'sinin hastalık özelliklerini gösterir. Translasyonel çalışmalar için, fare beyin tümörü in vivo MRG ve histopatoloji ile izlenir.

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