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JoVE Journal Cancer Research
Modelo murino espontáneo de cáncer anaplásico de tiroides
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Modelo murino espontáneo de cáncer anaplásico de tiroides

Article DOI: 10.3791/64607-v • 05:39 min • February 3rd, 2023
February 3rd, 2023 •
1, 1, 2, 3, 2, 4, 5, 1,6, 2,6
1State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center, 2Division of Thyroid Surgery, Laboratory of Thyroid and Parathyroid Disease, Frontiers Science Center for Disease-Related Molecular Network, Department of General Surgery, West China Hospital, Sichuan University, 3Department of Ultrasound, West China Hospital of Sichuan University, Sichuan University, 4Department of Otolaryngology-Head & Neck Surgery and University of Arizona Cancer Center, University of Arizona, 5Center for Translational Medicine, Shenzhen Bay Laboratory, 6Division of Laboratory Medicine/Research Centre of Clinical Laboratory Medicine, West China Hospital, Sichuan University

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Aquí, presentamos una tubería estándar para obtener tumores murinos ATC mediante modelos espontáneos de ratón genéticamente modificados. Además, presentamos la dinámica tumoral y la información patológica sobre las lesiones primarias y metastástasis. Este modelo ayudará a los investigadores a comprender la tumorigénesis y facilitar los descubrimientos de fármacos.

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Investigación del cáncer Número 192
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