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Tilrettelegging og fotoaktivering av prodrug-fargestoff nanoassemblies
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Tilrettelegging og fotoaktivering av prodrug-fargestoff nanoassemblies

Article DOI: 10.3791/64677-v • 08:54 min • February 17th, 2023
February 17th, 2023 •
1,2,3, 1,2,3, 1,2,3
1State Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong, 2Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 3Laboratory of Molecular Engineering and Nanomedicine, Dr. Li Dak-Sum Research Centre, The University of Hong Kong

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Denne protokollen beskriver fabrikasjon og karakterisering av en fotoresponsiv prodrug-fargestoff nanoassembly. Metodikken for frigjøring av legemidler fra nanopartiklene ved lysutløst demontering, inkludert lysbestrålingsoppsettet, er eksplisitt beskrevet. Legemidlene som ble frigjort fra nanopartiklene etter lysbestråling, viste gode anti-spredningseffekter på humane kolorektale tumorceller.

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