The protocol shows repeated cerebrospinal fluid and blood collections from epileptic rats performed in parallel with continuous video-electroencephalogram (EEG) monitoring. These are instrumental for exploring possible links between changes in various body fluid molecules and seizure activity.
Soukupová, M., Guarino, A., Asth, L., Marino, P., Barbieri, M., Simonato, M., Zucchini, S. Sampling Cerebrospinal Fluid and Blood from Lateral Tail Vein in Rats During EEG Recordings. J. Vis. Exp. (199), e65636, doi:10.3791/65636 (2023).