JoVE Journal
Biology
Biology
A subscription to JoVE is required to view this content.
Chapters
Summary
Please note that all translations are automatically generated.
Transgenic (Tg) mouse models of AD provide an excellent opportunity to investigate how and why Aβ or tau levels in CSF change as the disease progresses in human patients. Here, we demonstrate a refined cisterna magna puncture technique for serial CSF sampling from the mouse.