Journal
/
Medicine
/
Assessment of Right Ventricular Structure and Function in Mouse Model of Pulmonary Artery Constriction by Transthoracic Echocardiography
JoVE Journal
Medicine
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Medicine
Assessment of Right Ventricular Structure and Function in Mouse Model of Pulmonary Artery Constriction by Transthoracic Echocardiography

Assessment of Right Ventricular Structure and Function in Mouse Model of Pulmonary Artery Constriction by Transthoracic Echocardiography

DOI:
10.3791/51041-v

•

10:33 min

•

February 03, 2014

•

, , , , , , , , ,
1Cardiac Muscle Research Labratory, Cardiovascular Division, Brigham and Women’s Hospital,Harvard Medical School, 2Cardiovascular Department,Chang Gung Memorial Hospital

Chapters

  • 00:05Title
  • 01:39Surgical Procedure and Anesthesia
  • 02:42Echocardiographic Image Acquisition and Measurements
  • 07:06Data Calculation and Analysis
  • 08:16Results: Right Ventricular Structure and Function in Mice
  • 09:46Conclusion

Summary

Automatic Translation

Automatic Translation

Right ventricle (RV) dysfunction is critical to the pathogenesis of cardiovascular disease, yet limited methodologies are available for its evaluation. Recent advances in ultrasound imaging provide a noninvasive and accurate option for longitudinal RV study. Herein, we detail a step-by-step echocardiographic method using a murine model of RV pressure overload.

Tags

Right Ventricular StructureRight Ventricular FunctionPulmonary Artery ConstrictionTransthoracic EchocardiographyMouse ModelCardiac PathologyPressure GradientVentricular DysfunctionPulmonary Artery HypertensionNoninvasive AssessmentEchocardiographic Measurements

Article

Embed

ADD TO PLAYLIST

Usage Statistics

Related Videos

Transthoracic Echocardiography in Mice

Echocardiographic Assessment of the Right Heart in Mice

Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet

Assessment of Cardiac Morphological and Functional Changes in Mouse Model of Transverse Aortic Constriction by Echocardiographic Imaging

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation

Murine Echocardiography of Left Atrium, Aorta, and Pulmonary Artery

Echocardiographic Measurement of Right Ventricular Diastolic Parameters in Mouse

A Pulmonary Trunk Banding Model of Pressure Overload Induced Right Ventricular Hypertrophy and Failure

Isometric Contractility Measurement of the Mouse Mesenteric Artery Using Wire Myography

Invasive Hemodynamic Assessment for the Right Ventricular System and Hypoxia-Induced Pulmonary Arterial Hypertension in Mice

Read Article