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A Mouse Model of Subchronic and Mild Social Defeat Stress for Understanding Stress-induced Behavioral and Physiological Deficits
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Behavior
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JoVE Journal Behavior
A Mouse Model of Subchronic and Mild Social Defeat Stress for Understanding Stress-induced Behavioral and Physiological Deficits

A Mouse Model of Subchronic and Mild Social Defeat Stress for Understanding Stress-induced Behavioral and Physiological Deficits

DOI:
10.3791/52973-v

•

08:10 min

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November 24, 2015

•

,
1College of Agriculture,Ibaraki University, 2Cooperation between Agriculture and Medical Science,Ibaraki University, 3United Graduate School of Agricultural Science,Tokyo University of Agriculture and Technology

Chapters

  • 00:05Title
  • 01:09Habituating the Animal
  • 01:58Screening Aggressive ICR Mice
  • 02:57The sCSDS Model
  • 05:20Social Avoidance Test (Social Interaction Test)
  • 06:40Results: sCSDS Baseline Scores
  • 07:38Conclusion

Summary

Automatic Translation

Automatic Translation

Here, methods for developing a mouse model of subchronic and mild social defeat stress are described and used to investigate the pathogenic features of depression including hyperphagia- and polydipsia-like symptoms following increased body weight.

Tags

Mouse ModelSocial Defeat StressDepressionBehavioral DeficitsPhysiological DeficitsBody Weight GainFood IntakeWater IntakeSocial BehaviorAtypical DepressionStress-induced OvereatingStress-induced OverdrinkingChronic Social Defeat Stress

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