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Biochemistry

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JoVE Journal Biochemistry
En skräddarsydd HPLC reningsprotokoll som ger hög renhet Amyloid Beta 42 och Amyloid Beta 40 Peptider som kan oligomerbildning
High-throughput Screening of Carbohydrate-degrading Enzymes Using Novel Insoluble Chromogenic Substrate Assay Kits
Journal (Biochemistry)
High-throughput Screening of Carbohydrate-degrading Enzymes Using Novel Insoluble Chromogenic Substrate Assay Kits
Image Acquisition of Lipid Droplets and Analysis (Video) | JoVE
Journal (Biochemistry)
Image Acquisition of Lipid Droplets and Analysis (Video) | JoVE
 
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En skräddarsydd HPLC reningsprotokoll som ger hög renhet Amyloid Beta 42 och Amyloid Beta 40 Peptider som kan oligomerbildning

Article DOI: 10.3791/55482-v • 06:34 min • March 27th, 2017
March 27th, 2017 •
1, 1, 1, 1
1Department of Chemistry, University of California, Santa Cruz

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Häri rapporterar vi en skräddarsydd HPLC reningsprotokoll som ger hög renhet amyloid beta 42 (Aβ42) och amyloid beta 40 (Aβ40) peptider som kan oligomerbildning. Amyloid beta är en i hög grad aggregation benägen, hydrofob peptid inblandad i Alzheimers sjukdom. Den amyloidogeniska karaktären av peptiden gör dess rening en utmaning.

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Biokemi Amyloid beta Peptide Purification högupplösande vätskekromatografi Alzheimers sjukdom oligomerbildning picup
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