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JoVE Journal Genetics
Analyse des c-KIT-Liganden-Promotors unter Verwendung von Chromatin-Immunpräzipitation
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Analyse des c-KIT-Liganden-Promotors unter Verwendung von Chromatin-Immunpräzipitation

Article DOI: 10.3791/55689-v • 09:40 min • June 27th, 2017
June 27th, 2017 •
*1, *1, 1
1Department of Gastroenterology, Hepatology and Nutrition, The University of Texas MD Anderson Cancer Center
* These authors contributed equally

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DNA-Protein-Wechselwirkungen sind für mehrere biologische Prozesse essentiell. Bei der Auswertung von zellulären Funktionen ist die Analyse von DNA-Protein-Wechselwirkungen unentbehrlich für das Verständnis der Genregulation. Chromatin-Immunpräzipitation (ChIP) ist ein mächtiges Werkzeug, um solche Wechselwirkungen in vivo zu analysieren .

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Genetik Ausgabe 124 Chromatin-Immunpräzipitation Genregulation Promotor Transkriptionsfaktor c-KIT-Ligand TGF-β SMAD
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